Bipolar disorder is a highly heritable condition, which can progress from an asymptomatic period in at-risk individuals to a potentially debilitating illness. Identifying individuals who are at a high risk of developing bipolar disorder may provide an opportunity for early intervention to improve outcomes. The main objective of this systematic review is to provide an overview of prospective studies that evaluated the incidence and predictors of transitioning to bipolar disorder among high-risk individuals.
Advances in the pathophysiology of bipolar disorder
Bipolar disorder (BD) is a chronic and often severe psychiatric disorder affecting approximately 1–4%of the world population. There are three types of BD, including bipolar I disorder (BD-I), bipolar II disorder (BD-II), and cyclothymic disorder. All three types involve clear changes in mood, energy, and activity levels. Leer texto completo
