In some patients with SZ, a vulnerable brain endothelium may be interacting with environmental stressors, such as inflammation or hypoxia, converging into a more severe SZ symptomatology. Gene expression and performance of human brain endothelium could vary along with development and the establishment of the BBB; therefore, we encourage to investigate its possible contribution to SZ considering this dynamic context.
Advances in the pathophysiology of bipolar disorder
Bipolar disorder (BD) is a chronic and often severe psychiatric disorder affecting approximately 1–4%of the world population. There are three types of BD, including bipolar I disorder (BD-I), bipolar II disorder (BD-II), and cyclothymic disorder. All three types involve clear changes in mood, energy, and activity levels. Leer texto completo
