We advocate considering depression and personality as being more closely related and argue in favour of the development of integrated treatment options tailored to understanding symptoms as being interwoven with a variety of long-standing disturbing personality patterns. Both clinically and conceptually, psychodynamic and schema-focused approaches provide good opportunities to adjust available therapies and they could optimize outcomes in this complex patient group. Given the risk of treatment resistance and chronicity, a combination of psychotherapy and medication should always be considered.

Advances in the pathophysiology of bipolar disorder
Bipolar disorder (BD) is a chronic and often severe psychiatric disorder affecting approximately 1–4%of the world population. There are three types of BD, including bipolar I disorder (BD-I), bipolar II disorder (BD-II), and cyclothymic disorder. All three types involve clear changes in mood, energy, and activity levels. Leer texto completo
